Caldbeck Surgery: THE NEW US

On behalf of Caldbeck Surgery we would like to thank you for all your support during all this new changes.

Cumbria Sexual Health Clinic

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The PRINCIPLE Trial Evaluating potential treatments for COVID-19 in older people

We would like to invite you to take part in a study about treatments for COVID-19 infection called PRINCIPLE. Before you decide if you would like to take part it is important that you understand why we are doing this research and what it would involve for you. Please take time to read the information carefully and decide if you wish to take part. You may like to talk to others, friends or family members about the trial. Please ask if there is anything that is not clear or if you would like more information.    EudraCT number:2020-001209-22

The PRINCIPLE trial aims to find treatments for COVID-19 for older people. We want to find medicines that can help people with COVID-19 symptoms get better quickly and stop them needing to go to hospital. The trial is recruiting participants through this website

– About the trial

– Who can take part

– What the trial involves

– Why take part

Coronavirus disease 2019 (COVID-19) can be more severe in older people, and people with underlying health conditions. At the moment, there are no specific treatments that we know definitely work against COVID-19. We urgently need research to find medicines that help people get better quickly and stop them needing to go to hospital.

About the trial The PRINCIPLE trial is a national priority trial to find treatments for COVID-19. It is now a country-wide trial, and the only national priority platform trial in primary care. The trial is being run by the University of Oxford and is funded by UK Research and Innovation and the the Department for Health and Social Care through the National Institute for Health Research.

Aim of this trial We aim to find treatments for COVID-19 for people in the community who are at higher risk of complications. We want to find medicines that can help people get better quickly and stop them needing to go to hospital. In the first instance, we are testing a drug called hydroxychloroquine. This is a drug that is well known and has been used for many years around the world for conditions such as malaria and arthritis, but is not currently used to treat COVID-19.

Who can take part Participation is entirely voluntary. It is up to you to decide whether to take part in the trial or not. The decision to not take part will not affect the standard of care you receive from the NHS in any way, now or in the future. The trial is open to people aged 65 or over even without other illnesses who have symptoms of COVID-19. It is also open to those aged 50 to 64 who are experiencing symptoms that are likely to be caused by a COVID-19 infection and have at least one of the following conditions:

 A known weakened immune system because of a serious illness or medication (e.g. chemotherapy);

 Known heart disease or high blood pressure;

 Known asthma or lung disease;

  Known diabetes not treated with insulin;

 Known mild hepatic impairment (liver disease);

  Have previously had a stroke or have known neurological problems.

Symptoms of COVID-19:  a new, continuous cough  and/or a high temperature. These symptoms need to have been experienced for fewer than 15 days

What does the trial involve? Briefly, participants will need to answer some questions online or on the telephone (0800 138 0880) to check they are suitable, and provide consent. They will be able to nominate a ‘study partner’ (family, friend, carer) to help them with the study.

Their GP, or a study nurse or doctor, will also check their medical notes to make sure it is safe for them to be in the study.

They will either receive usual care, or usual care and a study drug which will be delivered from their GP, or directly from the research team. All study drugs are already widely used in the NHS and have been approved as safe for use in this study. The study will use a computer programme to decide by chance whether they get the drug or not.

They will have a swab done to test for COVID-19, if swabs are available. If they can access the internet, for the next 28 days we would like them to complete an online diary of their symptoms and medical care they have received. If they can’t access the internet, the trial team can phone them every one to two weeks to get this information

Why take part By taking part in this trial, you will be contributing towards the understanding of how we can treat COVID-19 and how the symptoms progress. This may or may not help to reduce the duration and severity of symptoms when people fall ill. We also hope to reduce the burden on the NHS.

Further information at

How to get the healthcare you need during the coronavirus outbreak

Published on 4 May 2020 Dr Mark Dornan explains how to get the healthcare you need during the coronavirus outbreak – and says if you do need help, please do .

In the video, Mark explains:

• How health and care services have had to adapt and we all need to use them differently

• Why we need you to prioritise looking after your own health at this time

• If you do need help, please don’t wait

Caldbeck Surgery is still open. Please call us if you need any medical advice.


From Caldbeck Surgery to everyone that is staying at home and staying safe.

Thank you for your support.

Shielding Advice

Shielding yourself is a very severe measure. It means not leaving your home for 12 weeks other than for essential medical care. It is only recommended for those with specific clinical conditions.

If you are confused about why you are not being advised to shield, you can look at these frequently asked questions You can also get in touch with your surgery if you wish to discuss the matter further.

You can also get in touch with the surgery if you wish to discuss the matter further.

Patients who are over 70 years old or have a condition that mean they would usually be offered an annual flu vaccination, for example anyone with asthma, COPD, or diabetes have an increased risk compared with the average healthy person. However, this risk is not big enough for the Government to advise everyone in this group to “shield”.

We recommend that you stringently follow the latest social distancing guidance to stay at home, not meet up with people outside your household, only go out once a day for exercise and maintain a two-meter distance with people outside your household.

We know this is a difficult time and you may be struggling to cope with your daily activities or accessing essentials. If this is the case, please get in touch with the local council who is working with the voluntary sector and others, to support you.

You can also ask for help from NHS Volunteer Responder scheme with short-term telephone support if you are feeling lonely, or for help with collecting shopping, medication or other essential supplies that you need delivered to your home. You can ask for help by calling 0808 1963646 between 8am-8pm.

If you haven’t already done so, please do continue to contact us by phone, email or online if you have concerns about your health.

You might also find the following sources of information useful:

• Local services

• Health at home has information about NHS services that are available such as how to order repeat prescriptions online and get them delivered  

• Government advice on Employment and financial support:   

• Looking after your mental health and wellbeing during the COVID-19 pandemic:

Find out what you can do if you’re struggling because of COVID-19

Find out what you can do if you’re struggling because of coronavirus (COVID-19)

Use this service to find out what help you can get if you’re affected by coronavirus. You can use it for yourself or someone else.

You can find information about:

•feeling unsafe

•going in to work

•paying bills or being unemployed

•getting food

•having somewhere to live

•mental health and wellbeing

You will not get direct support from the government or organisations through this service.

Ibuprofen and coronavirus

Ibuprofen and coronavirus (COVID-19) The Commission of Human Medicines (CHM) has been asked to review the safety of ibuprofen in patients with COVID-19. The Commission on Human Medicines’ Expert Working Group on coronavirus (COVID-19) has concluded that there is currently insufficient evidence to establish a link between use of ibuprofen, or other non-steroidal anti-inflammatory drugs (NSAIDs), and contracting or worsening of COVID-19.

Patients can take paracetamol or ibuprofen when self-medicating for symptoms of COVID-19, such as fever and headache, and should follow NHS advice if they have any questions or if symptoms get worse.

Taking ibuprofen

Patients should always read the patient information when taking over-the-counter medicines, such as ibuprofen and paracetamol, and follow the instructions on how to take the medicines.

Prescribing ibuprofen

Healthcare professionals should consider a patient’s individual risk factors, including any history of cardiovascular and gastrointestinal illness, when prescribing ibuprofen. Additionally, ibuprofen should be used with caution in patients with known renal impairment.

The lowest effective dose of ibuprofen should be used for the shortest duration necessary to control symptoms.

Patients who have been prescribed NSAIDs as a treatment for a long-term condition, such as arthritis, should keep taking these medicines as normal. Adult patients who take low-dose 75 mg aspirin regularly for prevention of heart attacks or for vascular disease should continue to do so.

 Dr June Raine  CBE Chief Executive,  , Medicines and Healthcare products  Regulatory Agency

Professor Stephen Powis, National Medical Director, NHS England and NHS Improvement

Professor Gilllian Leng CBE, Chief Executive, National Institute for Health and Care Excellence